Ethylene

Ethylene

SCHEMBL4438510

C=C.COC(=O)c1ccc(C(=O)OO)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA12 O43570 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
TDP1 Q9NUW8 1/20 0.61
TSHR P16473 1/20 0.58
MAPT P10636 5/20 0.56
RAB9A P51151 3/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
NPC1 O15118 2/20 0.56
MAPK1 P28482 2/20 0.56
HTT P42858 1/20 0.56
ALDH1A1 P00352 2/20 0.55
ATM Q13315 1/20 0.55
LOXL2 Q9Y4K0 1/20 0.53
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8154988 0.95 CA1 (0.67) CA1CA2CA12CA7CA9
Ethylene SCHEMBL8070484 0.91 CA1 (0.73) CA1CA2CA12CA7CA9
Ethylene SCHEMBL1366416 0.88 CES2 (0.43) CA1CA2CA12CA7CA9
SCHEMBL28993944 0.85 CA1 (0.80) CA1CA2CA12CA7CA9
SCHEMBL23600 0.85 CA1 (0.80) CA1CA2CA12CA7CA9
SCHEMBL63811 0.84 MAPT (0.75) CA1CA2CA12CA7CA9
Methyl Alcohol SCHEMBL28561085 0.83 CA1 (0.76) CA1CA2CA12CA7CA9
SCHEMBL28993277 0.83 CA1 (0.76) CA1CA2CA12CA7CA9
Water SCHEMBL22720573 0.83 CA1 (0.76) CA1CA2CA12CA7CA9
SCHEMBL28531063 0.83 CA1 (0.76) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4294859-B2 2009-07-15 JP claimed
JP-2002514661-A 2002-05-21 JP claimed
EP-1023369-A1 DEPOLYMERIZATION PROCESS FOR RECYCLING POLYESTERS EASTMAN CHEMICAL COMPANY (US) 2000-08-02 EP claimed
WO-1999020684-A1 DEPOLYMERIZATION PROCESS FOR RECYCLING POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1999-04-29 WO claimed