Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880295 | 0.85 | NPC1 (0.39) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL4439833 | 0.85 | NPC1 (0.54) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL4453092 | 0.83 | ELANE (0.43) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL93326 | 0.83 | NPC1 (0.52) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL29384504 | 0.83 | NPC1 (0.52) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL5178883 | 0.82 | NPC1 (0.39) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL4442083 | 0.81 | NPC1 (0.34) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL4992804 | 0.80 | NPC1 (0.35) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL3510761 | 0.80 | LMNA (0.36) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL4445498 | 0.80 | ELANE (0.36) | NPC1RAB9AKMT2AATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1256611-B1 | Aqueous dispersion and coated product | JSR CORP (JP) | 2009-07-29 | — | — | EP | disclosed |
| US-6726997-B2 | WWATERPROOF, HARDNESS, RATION TRANSPARENT; PROTECTIVE COATINGS | JSR CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20030073779-A1 | Aqueous dispersion and coated product | JSR CORPORATION (JP) | 2003-04-17 | — | — | US | disclosed |
| EP-1256611-A2 | Aqueous dispersion and coated product | JSR Corporation (JP) | 2002-11-13 | — | — | EP | disclosed |