Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11864950 | 0.76 | USP2 (0.49) | NPSR1ALDH1A1USP2SMN1; SMN2HPGD | |
| SCHEMBL1711899 | 0.73 | USP2 (0.46) | NPSR1ALDH1A1USP2SMN1; SMN2HPGD | |
| SCHEMBL1711900 | 0.73 | USP2 (0.46) | NPSR1ALDH1A1USP2SMN1; SMN2HPGD | |
| SCHEMBL1711904 | 0.73 | USP2 (0.46) | NPSR1ALDH1A1USP2SMN1; SMN2HPGD | |
| SCHEMBL4438745 | 0.72 | CPN1 (0.47) | ALDH1A1USP2SMN1; SMN2HPGDTP53 | |
| SCHEMBL499885 | 0.72 | NPSR1 (0.61) | NPSR1ALDH1A1USP2SMN1; SMN2HPGD | |
| SCHEMBL7888124 | 0.71 | USP2 (0.45) | ALDH1A1USP2SMN1; SMN2HPGDTP53 | |
| SCHEMBL1711638 | 0.71 | USP2 (0.45) | ALDH1A1USP2SMN1; SMN2HPGDTP53 | |
| SCHEMBL7888410 | 0.71 | USP2 (0.45) | ALDH1A1USP2SMN1; SMN2HPGDTP53 | |
| SCHEMBL7366756 | 0.71 | USP2 (0.45) | ALDH1A1USP2SMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263339-A1 | AGENT FOR EXTERNAL APPLICATION TO THE SKIN | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKY (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1894558-A1 | AGENT FOR EXTERNAL APPLICATION TO THE SKIN | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2008-03-05 | — | — | EP | disclosed |