Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991294 | 1.00 | MAPT (0.40) | MAPT | |
| SCHEMBL2988905 | 1.00 | MAPT (0.40) | MAPT | |
| SCHEMBL4439990 | 0.82 | TSHR (0.45) | — | |
| SCHEMBL2990188 | 0.82 | TSHR (0.45) | — | |
| SCHEMBL1218293 | 0.82 | TSHR (0.45) | — | |
| SCHEMBL2986943 | 0.80 | ALDH1A1 (0.50) | MAPT | |
| SCHEMBL2984392 | 0.80 | ALDH1A1 (0.50) | MAPT | |
| SCHEMBL25392616 | 0.80 | MAPT (0.50) | MAPT | |
| SCHEMBL1127763 | 0.80 | MAPT (0.50) | MAPT | |
| SCHEMBL18923856 | 0.79 | MAPT (0.43) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125702-A1 | LEVODOPA DIMETHYL-SUBSTITUTED DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | Xenoport, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079387-A1 | CATECHOL PROTECTED LEVODOPA DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008076458-A1 | LEVODOPA DIMETHYL-SUBSTITUTED DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2008-06-26 | — | — | WO | disclosed |