Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116533 | 0.68 | CYP19A1 (0.58) | TAAR1HTR1AALDH1A1MEN1KDM4A | |
| SCHEMBL2351887 | 0.67 | CYP19A1 (0.64) | CYP11B1CYP11B2 | |
| SCHEMBL31272207 | 0.67 | POLB (0.40) | HTR1AHTR2CALDH1A1MEN1MAPT | |
| SCHEMBL2563333 | 0.66 | TAAR1 (0.43) | TAAR1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4834371 | 0.65 | CYP19A1 (0.48) | ALDH1A1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL1491120 | 0.63 | KDM4E (0.59) | TAAR1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4701933 | 0.62 | ALDH1A1 (0.48) | TAAR1ALDH1A1KMT2ADRD2DRD3 | |
| SCHEMBL10674754 | 0.62 | HRH3 (0.56) | ALDH1A1L3MBTL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8671494 | 0.61 | TAAR1 (0.71) | TAAR1ADORA2AALDH1A1MEN1KDM4A | |
| SCHEMBL9369371 | 0.61 | CYP11B1 (0.61) | MAPTCYP17A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097410-A1 | HETEROARYL-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS | Green Cross Corporation (KR) | 2009-09-09 | — | — | EP | claimed |
| WO-2008039023-A1 | HETEROARYL-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS | GREEN CROSS CORPORATION (KR) | 2008-04-03 | — | — | WO | claimed |