Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.30 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | IL2 | P60568 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439716 | 0.95 | F2 (0.36) | F2PLGF10PLAUKLKB1 | |
| SCHEMBL4428156 | 0.94 | PLG (0.39) | F2PLGF10PLAUKLKB1 | |
| SCHEMBL4436533 | 0.94 | PLG (0.39) | F2PLGF10PLAUKLKB1 | |
| SCHEMBL4428164 | 0.94 | PLG (0.39) | F2PLGF10PLAUKLKB1 | |
| SCHEMBL4438792 | 0.93 | PLG (0.39) | F2PLGF10PLAUKLKB1 | |
| SCHEMBL4430769 | 0.92 | PLG (0.38) | F2PLGF10PLAUKLKB1 | |
| SCHEMBL4432506 | 0.92 | PLG (0.36) | F2PLGF10PLAUKLKB1 | |
| SCHEMBL4433216 | 0.92 | PLG (0.35) | F2PLGF10PLAUKLKB1 | |
| SCHEMBL4432533 | 0.91 | PLG (0.39) | F2PLGF10PLAUKLKB1 | |
| SCHEMBL4433285 | 0.91 | PLG (0.39) | F2PLGF10PLAUKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125739-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |