Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091388 | 1.00 | ABCG2 (0.51) | ABCG2CYP19A1MAPTALDH1A1ADORA3 | |
| SCHEMBL27817114 | 0.86 | ABCG2 (0.50) | ABCG2CYP19A1MAPTALDH1A1ADORA3 | |
| SCHEMBL1068877 | 0.85 | ALDH1A1 (0.50) | CYP19A1MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL29406099 | 0.85 | ALDH1A1 (0.50) | CYP19A1MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL18940919 | 0.81 | NPC1 (0.52) | ABCG2CYP19A1POLB | |
| SCHEMBL28002582 | 0.78 | NPC1 (0.42) | ABCG2CYP19A1MAPTALDH1A1KDM4E | |
| SCHEMBL28984268 | 0.78 | KDM4E (0.48) | ABCG2MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL27655154 | 0.76 | ALDH1A1 (0.50) | ABCG2CYP19A1MAPTALDH1A1ATM | |
| SCHEMBL3364490 | 0.75 | ABCG2 (0.54) | ABCG2CYP19A1MAPTALDH1A1ADORA3 | |
| SCHEMBL8355010 | 0.73 | RECQL (0.44) | CYP19A1MAPTALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429602-B1 | METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS | UNIV RUTGERS (US) | 2009-12-16 | — | — | EP | disclosed |
| EP-1429602-A4 | METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS | UNIV RUTGERS (US) | 2005-12-21 | — | — | EP | disclosed |
| US-6893627-B2 | Method for treating type 2 diabetes with an extract of Artemisia | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2005-05-17 | — | — | US | disclosed |
| US-20050069598-A1 | Methods for treating disorders using plant extracts | RIBNICKY DAVID M (US) | 2005-03-31 | — | — | US | disclosed |
| EP-1429602-A1 | METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2004-06-23 | — | — | EP | disclosed |
| US-20030072822-A1 | Methods for treating disorders using plant extracts | RUTGERS, THE STATE OF UNIVERSITY OF NEW JERSEY | 2003-04-17 | — | — | US | disclosed |
| WO-2003020026-A1 | METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2003-03-13 | — | — | WO | disclosed |