Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2816886 | 0.93 | MAPT (0.59) | MAPTL3MBTL1RXFP1HDAC1HDAC2 | |
| SCHEMBL4440458 | 0.91 | MAPT (0.52) | MAPTL3MBTL1RXFP1HDAC1HDAC2 | |
| SCHEMBL4437667 | 0.82 | NR1H4 (0.47) | MAPTKMT2AMEN1KDM4EPOLB | |
| SCHEMBL4556216 | 0.81 | MAPT (0.45) | MAPTL3MBTL1RXFP1KMT2AMEN1 | |
| SCHEMBL2817530 | 0.80 | MCHR1 (0.50) | MAPTL3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL2814444 | 0.78 | KMT2A (0.62) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL2813529 | 0.78 | MAPT (0.57) | MAPTL3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL2814683 | 0.77 | NPC1 (0.58) | MAPTKMT2AMEN1KDM4EPOLB | |
| SCHEMBL2817390 | 0.77 | POLB (0.51) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL2818888 | 0.77 | MAPT (0.48) | MAPTL3MBTL1HDAC1HDAC2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |