Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2816886 | 0.91 | MAPT (0.59) | MAPTL3MBTL1RXFP1HDAC1HDAC2 | |
| SCHEMBL4440455 | 0.91 | MAPT (0.53) | MAPTL3MBTL1RXFP1HDAC1HDAC2 | |
| SCHEMBL4437668 | 0.83 | NPC1 (0.45) | MAPTTP53KMT2AMEN1KDM4E | |
| SCHEMBL4556216 | 0.79 | MAPT (0.45) | MAPTL3MBTL1RXFP1KMT2AMEN1 | |
| SCHEMBL2814428 | 0.79 | KMT2A (0.60) | MAPTTP53KMT2AMEN1POLB | |
| SCHEMBL2817530 | 0.77 | MCHR1 (0.50) | MAPTL3MBTL1TP53KMT2AMEN1 | |
| SCHEMBL2813529 | 0.77 | MAPT (0.57) | MAPTL3MBTL1TP53KMT2AMEN1 | |
| SCHEMBL2818888 | 0.76 | MAPT (0.48) | MAPTL3MBTL1HDAC1HDAC2TP53 | |
| SCHEMBL2817842 | 0.75 | MEN1 (0.58) | MAPTL3MBTL1TP53KMT2AMEN1 | |
| SCHEMBL2815613 | 0.75 | NPC1 (0.57) | MAPTL3MBTL1TP53KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |