⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185868 | 0.70 | — | — | |
| SCHEMBL7892671 | 0.67 | — | — | |
| SCHEMBL28131368 | 0.65 | — | — | |
| SCHEMBL28154865 | 0.60 | — | — | |
| SCHEMBL28638745 | 0.60 | — | — | |
| SCHEMBL31310667 | 0.51 | — | — | |
| SCHEMBL11178675 | 0.47 | — | — | |
| SCHEMBL27467898 | 0.43 | — | — | |
| SCHEMBL26660960 | 0.43 | — | — | |
| SCHEMBL7465432 | 0.34 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110944668-A | Medicament comprising an mTOR inhibitor for treating or preventing ocular symptoms, disorders or diseases and uses thereof | 学校法人同志社 | 2020-03-31 | — | — | CN | disclosed |
| CN-109715205-A | RNA use for cancer treatment | 库瑞瓦格股份公司 | 2019-05-03 | — | — | CN | disclosed |
| US-8367627-B2 | Focused libraries, functional profiling, laser SELEX, and DESELEX | DUKE UNIVERSITY (US) | 2013-02-05 | — | — | US | disclosed |
| US-20090264508-A1 | Focused Libraries, Functional Profiling, Laser Selex, and Deselex | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-22 | — | — | US | disclosed |
| EP-1931803-A2 | FOCUSED LIBRARIES, FUNCTIONAL PROFILING, LASER SELEX AND DESELEX | DUKE UNIVERSITY (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007035532-A2 | FOCUSED LIBRARIES, FUNCTIONAL PROFILING, LASER SELEX AND DESELEX | DUKE UNIVERSITY (US) | 2007-03-29 | — | — | WO | disclosed |