⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29060433 | 0.71 | — | — | |
| SCHEMBL9223567 | 0.68 | — | — | |
| SCHEMBL3486076 | 0.68 | — | — | |
| SCHEMBL18569705 | 0.54 | — | — | |
| SCHEMBL7892671 | 0.53 | — | — | |
| SCHEMBL4440463 | 0.51 | — | — | |
| SCHEMBL28185868 | 0.51 | — | — | |
| SCHEMBL21305114 | 0.43 | — | — | |
| SCHEMBL21305084 | 0.40 | — | — | |
| SCHEMBL16002311 | 0.39 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119662650-A | RNAi agents for inhibiting alpha-ENaC expression and methods of use | 箭头药业股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-110832077-B | RNAi agents for inhibiting alpha-ENaC expression and methods of use | 箭头药业股份有限公司 | 2025-01-03 | — | — | CN | disclosed |