Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.61 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764691 | 0.74 | CCR3 (0.67) | CARM1PRMT6SIGMAR1GRIN2BCCR3 | |
| SCHEMBL4864451 | 0.73 | CARM1 (0.61) | CARM1PRMT6DRD4 | |
| SCHEMBL14318735 | 0.73 | BACE1 (0.50) | CARM1PRMT6SIGMAR1DRD2 | |
| SCHEMBL7032512 | 0.72 | CARM1 (0.57) | CARM1PRMT6ACHE | |
| SCHEMBL27843918 | 0.72 | CARM1 (0.62) | CARM1PRMT6DRD4SIGMAR1DRD2 | |
| SCHEMBL102816 | 0.70 | CARM1 (0.50) | CARM1PRMT6DRD4GRIN2BGRIN1 | |
| SCHEMBL12110641 | 0.70 | CARM1 (0.50) | CARM1PRMT6DRD4GRIN2BGRIN1 | |
| SCHEMBL3011074 | 0.70 | CARM1 (0.53) | CARM1PRMT6DRD4GRIN2BGRIN2A | |
| SCHEMBL4870804 | 0.70 | GRIN2A (0.54) | CARM1PRMT6GRIN2BGRIN2AACHE | |
| SCHEMBL14307093 | 0.70 | CHRM2 (0.60) | DRD4SIGMAR1DRD2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021005-A1 | METHODS AND COMPOSITION FOR TREATMENT OF INFLAMMATORY PAIN | CNSBIO PTY LTD (AU) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007128056-A1 | METHODS AND COMPOSITION FOR TREATMENT OF INFLAMMATORY PAIN | CNSBIO PTY LTD (AU) | 2007-11-15 | — | — | WO | disclosed |