Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.61 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886997 | 0.89 | CARM1 (0.54) | CARM1PRMT6SMN1; SMN2KDM1ACHRM1 | |
| SCHEMBL12049742 | 0.82 | KMT2A (0.45) | CARM1PRMT6SMN1; SMN2CYP2D6KDM4E | |
| SCHEMBL4874579 | 0.81 | GAA (0.44) | CARM1PRMT6SMN1; SMN2KDM1AKDM4E | |
| SCHEMBL12676793 | 0.81 | CARM1 (0.43) | CARM1PRMT6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4612660 | 0.81 | CARM1 (0.43) | CARM1PRMT6SMN1; SMN2KDM1ACHRM1 | |
| SCHEMBL18758727 | 0.81 | POLB (0.50) | CARM1PRMT6SLC6A3HTR2AHTR2C | |
| SCHEMBL14081453 | 0.81 | CARM1 (0.43) | CARM1PRMT6SMN1; SMN2HRH3MAOB | |
| SCHEMBL14082390 | 0.81 | CARM1 (0.43) | CARM1PRMT6SMN1; SMN2CYP2D6DRD1 | |
| SCHEMBL102816 | 0.80 | CARM1 (0.50) | CARM1PRMT6SMN1; SMN2MAPK1MAOB | |
| SCHEMBL12110641 | 0.80 | CARM1 (0.50) | CARM1PRMT6SMN1; SMN2MAPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-7408067-B2 | Aza-cyclic compounds as modulators of acetylcholine receptors | MERCK + CO., INC. (US) | 2008-08-05 | — | — | US | disclosed |
| EP-1467986-A1 | AZA-CYCLIC COMPOUNDS AS MODULATORS OF ACETYLCHOLINE RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003062224-A1 | AZA-CYCLIC COMPOUNDS AS MODULATORS OF ACETYLCHOLINE RECEPTORS | ELI LILLY AND COMPANY (US) | 2003-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NOX1, CBR1, AOX1 | CARM1 1997/4885PRMT6 2852/4885SMN1; SMN2 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.