⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440803 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL814297 | 0.66 | — | — | |
| SCHEMBL815409 | 0.66 | — | — | |
| SCHEMBL534394 | 0.66 | — | — | |
| SCHEMBL1358665 | 0.62 | — | — | |
| SCHEMBL3137830 | 0.61 | — | — | |
| SCHEMBL2486892 | 0.60 | — | — | |
| SCHEMBL12287931 | 0.58 | TSHR (0.44) | — | |
| SCHEMBL2429628 | 0.58 | — | — | |
| SCHEMBL14776723 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276781-B1 | ETHYLENE-TETRAFLUOROETHYLENE INTERMEDIATES | DU PONT (US) | 2012-11-07 | — | — | EP | disclosed |
| US-8212064-B2 | Ethylene tetrafluoroethylene intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-03 | — | — | US | disclosed |
| US-20090287010-A1 | Ethylene-tetrafluoroethylene intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-19 | — | — | US | disclosed |