Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13379049 | 0.90 | PTPN1 (0.48) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL3833437 | 0.90 | PTPN1 (0.48) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL10522832 | 0.90 | PTPN1 (0.48) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL15866138 | 0.84 | PTPN1 (0.45) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL9846453 | 0.84 | PTPN1 (0.45) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL5745374 | 0.84 | PTPN1 (0.45) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL18453426 | 0.83 | PTPN1 (0.44) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL13567845 | 0.82 | PTPN1 (0.43) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL6358667 | 0.81 | PTPN1 (0.42) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL22211568 | 0.81 | PTPN1 (0.42) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137184-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008124323-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-10-16 | — | — | WO | disclosed |