Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 11/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773156 | 1.00 | FKBP1A (0.50) | FKBP1AHSD17B10TLR2TLR1SMN1; SMN2 | |
| SCHEMBL18676059 | 0.95 | FKBP1A (0.52) | FKBP1AHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12215284 | 0.95 | FKBP1A (0.52) | FKBP1AHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20609369 | 0.91 | TLR2 (0.44) | FKBP1AHSD17B10TLR2TLR1MEN1 | |
| SCHEMBL2760258 | 0.91 | FKBP1A (0.55) | FKBP1AHSD17B10 | |
| SCHEMBL18675971 | 0.89 | FKBP1A (0.50) | FKBP1AHSD17B10TLR2TLR1SMN1; SMN2 | |
| SCHEMBL18668954 | 0.89 | FKBP1A (0.50) | FKBP1AHSD17B10TLR2TLR1SMN1; SMN2 | |
| SCHEMBL25960272 | 0.87 | FKBP1A (0.50) | FKBP1AHSD17B10TLR2TLR1SMN1; SMN2 | |
| SCHEMBL26539682 | 0.87 | TLR2 (0.42) | FKBP1AHSD17B10TLR2TLR1SMN1; SMN2 | |
| SCHEMBL15911990 | 0.86 | FKBP1A (0.49) | FKBP1AHSD17B10TLR2TLR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125695-A2 | NITRIC OXIDE DONOR COMPOUNDS | Nicox S.A. (FR) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |