SCHEMBL4441968

SCHEMBL4441968

CNc1ccccc1.CO[SiH](C)OC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.64
KDM1A O60341 1/20 0.36
TDP1 Q9NUW8 4/20 0.36
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
CTSD P07339 1/20 0.36
PTGS2 P35354 2/20 0.35
ALOX15 P16050 2/20 0.35
MAPK1 P28482 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALOX12 P18054 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2B P41595 1/20 0.35
IDO1 P14902 3/20 0.33
LMNA P02545 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
HPGD P15428 2/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142327 0.84 TSHR (0.67) TSHRKDM1ATDP1ALDH1A1HSD17B10
SCHEMBL16610513 0.83 TSHR (0.82) TSHRKDM1ATDP1ALDH1A1HSD17B10
SCHEMBL4454 0.80
SCHEMBL3008675 0.80
SCHEMBL19298582 0.80 TSHR (1.00) TSHRKDM1ATDP1ALDH1A1HSD17B10
Benzene SCHEMBL17977991 0.80 TSHR (1.00) TSHRKDM1ATDP1ALDH1A1HSD17B10
SCHEMBL11220257 0.77 TSHR (0.93) TSHRKDM1ATDP1ALDH1A1HSD17B10
Ammonia Solution, Strong SCHEMBL7932140 0.77
Iodide SCHEMBL22092509 0.77
Phosphine SCHEMBL11220255 0.77 TSHR (0.93) TSHRKDM1ATDP1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001618-B Moisture curable polymer system based on mixtures of polysilanated polyethers 陶氏环球技术有限责任公司 2020-07-03 CN disclosed
US-10239998-B2 Moisture curable polymer systems based on a mixture of polysilylated polyethers DOW GLOBAL TECHNOLOGIES LLC (US) 2019-03-26 US disclosed
EP-3237489-B1 MOISTURE CURABLE POLYMER SYSTEMS BASED ON A MIXTURE OF POLYSILYLATED POLYETHERS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-01-30 EP disclosed
US-20170369648-A1 Moisture Curable Polymer Systems Based on a Mixture of Polysilylated Polyethers DOW GLOBAL TECHNOLOGIES LLC 2017-12-28 US disclosed
EP-3237489-A1 MOISTURE CURABLE POLYMER SYSTEMS BASED ON A MIXTURE OF POLYSILYLATED POLYETHERS Dow Global Technologies LLC (US) 2017-11-01 EP disclosed
WO-2016105915-A1 MOISTURE CURABLE POLYMER SYSTEMS BASED ON A MIXTURE OF POLYSILYLATED POLYETHERS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-30 WO disclosed
CN-103748128-B Based on the crosslinkable materials of organoxysilanes terminated polymer WACKER CHEMIE AG (DE) 2015-08-12 CN disclosed
US-8907027-B2 Cross-linkable materials based on organyl oxysilane-terminated polymers WACKER CHEMIE AG (DE) 2014-12-09 US disclosed
US-20140155545-A1 CROSS-LINKABLE MATERIALS BASED ON ORGANYL OXYSILANE-TERMINATED POLYMERS WACKER CHEMIE AG (DE) 2014-06-05 US disclosed
US-8642708-B2 Silane-crosslinking compositions WACKER CHEMIE AG (DE) 2014-02-04 US disclosed
US-20130102738-A1 SILANE-CROSSLINKING COMPOSITIONS WACKER CHEMIE AG (DE) 2013-04-25 US disclosed
US-20120165493-A1 ISOCYANATE-FREE SILANE-CROSSLINKING COMPOUNDS WACKER CHEMIE AG (DE) 2012-06-28 US disclosed
US-7550517-B2 Expandable mixtures that are devoid of isocyanates WACKER CHEMIE AG (DE) 2009-06-23 US disclosed
US-20060189705-A1 Expandable mixtures that are devoid of isocyanates WACKER CHEMIE AG (DE) 2006-08-24 US disclosed
US-20060084711-A1 Foaming mixtures WACKER CHEMIE AG (DE) 2006-04-20 US disclosed