Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638683 | 0.75 | MAPT (0.49) | KMT2ANPC1RAB9AHTTALDH1A1 | |
| SCHEMBL1639486 | 0.75 | MAPT (0.49) | KMT2ANPC1RAB9AHTTALDH1A1 | |
| SCHEMBL15090913 | 0.72 | KMT2A (0.40) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL23354382 | 0.71 | KMT2A (0.49) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL16865849 | 0.70 | KMT2A (0.51) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL2632661 | 0.70 | KMT2A (0.51) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL20488237 | 0.69 | KMT2A (0.48) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL7899244 | 0.69 | KMT2A (0.63) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL4447520 | 0.68 | ERCC5 (0.53) | KMT2AL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL23354197 | 0.67 | KMT2A (0.53) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962677-B2 | Methods of restoring cognitive ability using non-peptidic compounds | ACUMEN PHARMACEUTICALS, INC. (US) | 2015-02-24 | — | — | US | claimed |
| EP-2173340-B1 | METHODS OF ENHANCING COGNITIVE FUNCTION USING NON-PEPTIDIC COMPOUNDS | ACUMEN PHARMACEUTICALS INC (US) | 2013-07-10 | — | — | EP | claimed |
| US-8962677-B2 | Methods of restoring cognitive ability using non-peptidic compounds | ACUMEN PHARMACEUTICALS, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20090018084-A1 | METHODS OF RESTORING COGNITIVE ABILITY USING NON-PEPTIDIC COMPOUNDS | ACUMEN PHARMACEUTICALS, INC. | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018084-A1 | METHODS OF RESTORING COGNITIVE ABILITY USING NON-PEPTIDIC COMPOUNDS | BCHE, APP, ACHE | KMT2A 2509/4885L3MBTL1 179/4885NPC1 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.