Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | GSK3A | P49840 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2546850 | 0.80 | MAPT (0.37) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL16752590 | 0.77 | MEN1 (0.35) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL1043064 | 0.72 | MAPT (0.49) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL1535280 | 0.69 | GSK3A (0.52) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL79670 | 0.67 | KMT2A (0.53) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL5489285 | 0.66 | GSK3A (0.52) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL5484818 | 0.65 | GSK3A (0.52) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL5554090 | 0.65 | MAPT (0.44) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL2319507 | 0.65 | KMT2A (0.47) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL9354113 | 0.64 | MAPT (0.47) | MAPTALDH1A1POLBRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084001-B2 | Photoluminescent silica-based sensors and methods of use | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| EP-1877772-A4 | PHOTOLUMINESCENT SILICA-BASED SENSORS AND METHODS OF USE | CORNELL RES FOUNDATION INC (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-1877772-A2 | PHOTOLUMINESCENT SILICA-BASED SENSORS AND METHODS OF USE | CORNELL RESEARCH FOUNDATION, INC. (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006119087-A2 | PHOTOLUMINESCENT SILICA-BASED SENSORS AND METHODS OF USE | CORNELL RESEARCH FOUNDATION, INC. (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20060245971-A1 | Photoluminescent silica-based sensors and methods of use | NATIONAL SCIENCE FOUNDATION | 2006-11-02 | — | — | US | disclosed |