Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752590 | 0.86 | MEN1 (0.35) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL4443839 | 0.80 | MAPT (0.40) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL1043064 | 0.69 | MAPT (0.49) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL1535280 | 0.66 | GSK3A (0.52) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL5484818 | 0.62 | GSK3A (0.52) | MAPTALDH1A1POLBRECQLTDP1 | |
| Isothiocyanate SCHEMBL4409683 | 0.61 | KMT2A (0.46) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL9651432 | 0.60 | KMT2A (0.58) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL4427684 | 0.60 | HSD17B10 (0.55) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL25573 | 0.60 | GSK3A (0.47) | MAPTALDH1A1POLBRECQLTDP1 | |
| SCHEMBL6790202 | 0.59 | GSK3A (0.56) | MAPTALDH1A1POLBRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263037-A1 | POLYMERIC MATERIALS INCORPORATING CORE-SHELL SILICA NANOPARTICLES | CORNELL UNIVERSITY | 2011-10-27 | — | — | US | disclosed |
| WO-2009140266-A2 | POLYMERIC MATERIALS INCORPORATING CORE-SHELL SILICA NANOPARTICLES | CORNELL UNIVERSITY (US) | 2009-11-19 | — | — | WO | disclosed |