Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR10 | P46092 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12116808 | 0.92 | CCR10 (0.76) | CCR10 | |
| SCHEMBL1033444 | 0.90 | CCR10 (0.85) | CCR10 | |
| SCHEMBL1313835 | 0.89 | CCR10 (1.00) | CCR10 | |
| SCHEMBL1310789 | 0.89 | CCR10 (1.00) | CCR10 | |
| SCHEMBL1037568 | 0.88 | CCR10 (0.79) | CCR10 | |
| SCHEMBL1313952 | 0.88 | CCR10 (0.86) | CCR10 | |
| SCHEMBL1077770 | 0.88 | CCR10 (0.78) | CCR10 | |
| SCHEMBL1037564 | 0.87 | CCR10 (0.85) | CCR10 | |
| SCHEMBL1073504 | 0.87 | CCR10 (0.88) | CCR10 | |
| SCHEMBL1312516 | 0.87 | CCR10 (0.85) | CCR10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586748-B2 | 2-sulfonylamino-4-heteroaryl butyramide antagonists of CCR10 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-11-19 | — | — | US | disclosed |
| WO-2009126675-A1 | 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |