Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL223098 | 0.99 | KMT2A (0.41) | KCNH2HRH3RAB9AKMT2AGAA | |
| SCHEMBL223649 | 0.93 | KCNH2 (0.46) | KCNH2HRH3RAB9AKMT2AGAA | |
| SCHEMBL223654 | 0.92 | KMT2A (0.46) | KCNH2HRH3RAB9AKMT2AGAA | |
| Trifluoroacetic Acid SCHEMBL222396 | 0.89 | HRH3 (0.35) | KCNH2HRH3RAB9AHTT | |
| Trifluoroacetic Acid SCHEMBL2421558 | 0.87 | KDM4E (0.52) | ALDH1A1MAPTTSHRHTT | |
| Trifluoroacetic Acid SCHEMBL222744 | 0.86 | RAB9A (0.41) | HRH3RAB9AKMT2AALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL219824 | 0.85 | NPC1 (0.43) | KCNH2HRH3RAB9AKMT2AALDH1A1 | |
| Cyclohexane SCHEMBL2428515 | 0.84 | HRH3 (0.40) | KCNH2HRH3RAB9ATHRB | |
| Trifluoroacetic Acid SCHEMBL222702 | 0.82 | HRH3 (0.35) | KCNH2HRH3RAB9AKMT2ACCR8 | |
| Trifluoroacetic Acid SCHEMBL2417740 | 0.82 | NTRK1 (0.38) | KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065234-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-15 | — | — | US | disclosed |
| EP-2212283-B1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2011-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065234-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | HRH3, HRH4, CNR1 | KCNH2 1508/4885HRH3 1/4885RAB9A 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.