Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911433 | 1.00 | TBXAS1 (0.51) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 | |
| SCHEMBL2555641 | 0.98 | TBXAS1 (0.54) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 | |
| SCHEMBL1290373 | 0.98 | TBXAS1 (0.54) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 | |
| SCHEMBL2548840 | 0.98 | TBXAS1 (0.54) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 | |
| SCHEMBL2552649 | 0.98 | TBXAS1 (0.54) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 | |
| SCHEMBL2554332 | 0.98 | TBXAS1 (0.54) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 | |
| SCHEMBL1518057 | 0.98 | TBXAS1 (0.54) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 | |
| SCHEMBL2552091 | 0.98 | TBXAS1 (0.54) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 | |
| SCHEMBL2550963 | 0.98 | TBXAS1 (0.54) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 | |
| SCHEMBL2551104 | 0.98 | TBXAS1 (0.54) | TBXAS1CYP2C19ASAH1ALDH1A1ACER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2126065-A2 | ISOFORMS OF PIG LIVER ESTERASE | Evonik Degussa GmbH (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008116745-A2 | ISOFORMS OF PIG LIVER ESTERASE | EVONIK DEGUSSA GMBH (DE) | 2008-10-02 | — | — | WO | disclosed |