Dimethylformamide

Dimethylformamide

SCHEMBL4444469

CN(C)C=O.COC(=O)Cl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ALDH1A1 P00352 2/20 0.38
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylformamide SCHEMBL11675630 0.82
Dimethylformamide SCHEMBL27566667 0.80 TSHR (0.53) TSHRALDH1A1KEAP1NFE2L2HCAR2
Dimethylformamide SCHEMBL18338733 0.80 ALDH1A1 (0.59) TSHRALDH1A1KEAP1NFE2L2HCAR2
Dimethylformamide SCHEMBL11551151 0.79
Dimethylformamide SCHEMBL1221823 0.79 TSHR (0.60) TSHRALDH1A1TDP1
Dimethylformamide SCHEMBL29212684 0.79
SCHEMBL27737320 0.78 ALDH1A1 (0.50) TSHRALDH1A1KEAP1NFE2L2HCAR2
SCHEMBL3025 0.78
Tetrachloroethylene SCHEMBL28058160 0.76 TSHR (0.64) TSHRALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL18490013 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426365-B9 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME MITSUI CHEMICALS AGRO INC (JP) 2009-10-21 EP disclosed
EP-1426365-B1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME SANKYO AGRO CO LTD (JP) 2009-07-15 EP disclosed