SCHEMBL4444503

SCHEMBL4444503

CCO[Si](C)(CCCC(O)=S)OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3910135 0.94
SCHEMBL28420164 0.87 CES2 (0.36)
SCHEMBL4450916 0.87
SCHEMBL28992390 0.83
SCHEMBL4439647 0.81
SCHEMBL2046598 0.79 AKR1B1 (0.43)
SCHEMBL4443236 0.78
SCHEMBL1243888 0.77 CES2 (0.33)
SCHEMBL646411 0.77
SCHEMBL704022 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218165-A1 POLYMER-FILLER COMPOSITES WITH GUAYULE RUBBER BRIDGESTONE CORPORATION (JP) 2024-07-04 US disclosed
US-12006422-B2 Coupled polymer products, methods of making and compositions containing BRIDGESTONE CORPORATION (JP) 2024-06-11 US disclosed
US-20240117159-A1 Tire Having Tread Of Specified Rubber Composition And Related Methods BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2024-04-11 US disclosed
US-20240110055-A1 RESIN-EXTENDED RUBBER AND PROCESS FOR PREPARING BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2024-04-04 US disclosed
US-11932759-B1 Polymer-filler composites with guayule rubber BRIDGESTONE CORPORATION (JP) 2024-03-19 US disclosed
US-20240059800-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2024-02-22 US disclosed
EP-3724244-B1 FUNCTIONALIZED POLYMER, PROCESS FOR PREPARING AND RUBBER COMPOSITIONS CONTAINING THE FUNCTIONALIZED POLYMER BRIDGESTONE CORP (JP) 2024-02-21 EP disclosed
US-20240052139-A1 TIRE RUBBER COMPOSITIONS COMBINING BAGASSE-CONTAINING GUAYULE RUBBER WITH SILANE AND RELATED METHODS BRIDGESTONE CORPORATION (JP) 2024-02-15 US disclosed
US-11834573-B2 Resin-extended rubber and process for preparing BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2023-12-05 US disclosed
US-20230374278-A1 Tire Tread Rubber Composition And Related Methods BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2023-11-23 US disclosed
WO-2016048935-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2016-03-31 WO disclosed
US-20150315362-A1 RUBBER COMPOSITION WITH IMIDAZOLE-BASED SILICA SHIELDING AGENT BRIDGESTONE CORPORATION (JP) 2015-11-05 US disclosed
US-20150274939-A1 Rubber Compositions Comprising Metal Carboxylates And Processes For Making The Same BRIDGESTONE CORPORATION (JP) 2015-10-01 US disclosed
EP-2914654-A1 RUBBER COMPOSITIONS COMPRISING METAL CARBOXYLATES AND PROCESSES FOR MAKING THE SAME Bridgestone Corporation (JP) 2015-09-09 EP disclosed
WO-2014071301-A1 RUBBER COMPOSITIONS COMPRISING METAL CARBOXYLATES AND PROCESSES FOR MAKING THE SAME BRIDGESTONE CORPORATION (JP) 2014-05-08 WO disclosed
US-7592384-B2 Elatomeric composition containing multiple silane coupling agents BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2009-09-22 US disclosed
US-20080161458-A1 Elastomeric composition containing multiple silane coupling agents BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2008-07-03 US disclosed
US-7256231-B2 Silica-reinforced rubber compounded with blocked mercaptosilanes and alkyl alkoxysilanes BRIDGESTONE CORPORATION (JP) 2007-08-14 US disclosed
CN-1845930-A Method for producing thiocarboxylate silane GEN ELECTRIC (US) 2006-10-11 CN disclosed
US-20060106143-A1 Silica-reinforced rubber compounded with blocked mercaptosilanes and alkyl alkoxysilanes BRIDGESTONE CORPORATION 2006-05-18 US disclosed