Tribenuron Methyl

Tribenuron Methyl

SCHEMBL4444686

COC(=O)c1ccccc1S(=O)(=O)NC(=O)N(C)c1nc(C)nc(OC)n1.COC(=O)c1sccc1S(=O)(=O)NC(=O)Nc1nc(C)nc(OC)n1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 3/20 0.36
NPC1 O15118 2/20 0.35
PPARG P37231 1/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.34
CCR2 P41597 1/20 0.34
CDK1 P06493 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tribenuron Methyl SCHEMBL18489666 1.00 EDNRA (0.36) EDNRANPC1PPARGPPARDPPARA
SCHEMBL3429952 0.91 MAPT (0.36) EDNRANPC1KDM4EALDH1A1MAPT
SCHEMBL3429264 0.91 MAPT (0.36) EDNRANPC1KDM4EALDH1A1MAPT
Sulfometuron Methyl SCHEMBL7635126 0.89 PPARG (0.39) EDNRANPC1PPARGPPARDPPARA
Thifensulfuron-Methyl SCHEMBL29463414 0.86 EDNRA (0.46) EDNRANPC1PPARGPPARDPPARA
Thifensulfuron-Methyl SCHEMBL9139398 0.86 EDNRA (0.46) EDNRANPC1PPARGPPARDPPARA
Thifensulfuron-Methyl SCHEMBL20723624 0.86 EDNRA (0.46) EDNRANPC1PPARGPPARDPPARA
Thifensulfuron-Methyl SCHEMBL53606 0.86 EDNRA (0.46) EDNRANPC1PPARGPPARDPPARA
Tribenuron Methyl SCHEMBL30438049 0.85 KMT2A (0.43) NPC1GAAMAPTMEN1KMT2A
Tribenuron Methyl SCHEMBL54532 0.85 KMT2A (0.43) NPC1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170042155-A1 USE OF 3-ISOXAZOLIDINONES COMPOUNDS AS SELECTIVE HERBICIDES FMC CORPORATION 2017-02-16 US disclosed
US-7632782-B2 4-(2-Methyl-3-(4,5-dihydroisoxazol-3-yl)-4-methylsulfonyl-benzoyl)-1-methyl-5-hydroxy-1H-pyrazole and a sulfonylurea herbicide of the formula 1-(((2-dimethylamido-),4-(carbonylamino-)phenyl)-sulfonyl-),3-((4,6-dimethoxy-)pyrimidin-2-yl)urea; cropprotection; increased activity and/or selectivity BASF AKTIENGESELLSCHAFT (DE) 2009-12-15 US disclosed
US-20060166828-A1 Synergistically acting herbicidal mixtures BASF AKTIENGSELLSCHAFT (DE) 2006-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060166828-A1 Synergistically acting herbicidal mixtures GLRX3, DDT, CBR3 EDNRA 3526/4885NPC1 4399/4885PPARG 705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.