SCHEMBL3429264

SCHEMBL3429264

COc1nc(C)nc(N(C)C(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccsc2C(=O)O)n1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
EDNRA P25101 6/20 0.34
EDNRB P24530 1/20 0.34
CDK1 P06493 1/20 0.33
FABP4 P15090 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3429952 1.00 MAPT (0.36) MAPTKDM4ENPC1ALDH1A1EDNRA
Tribenuron Methyl SCHEMBL4444686 0.91 EDNRA (0.36) MAPTKDM4ENPC1ALDH1A1EDNRA
Tribenuron Methyl SCHEMBL18489666 0.91 EDNRA (0.36) MAPTKDM4ENPC1ALDH1A1EDNRA
SCHEMBL9715135 0.86 EDNRA (0.43) MAPTKDM4ENPC1ALDH1A1EDNRA
SCHEMBL29397121 0.86 EDNRA (0.43) MAPTKDM4ENPC1ALDH1A1EDNRA
SCHEMBL65522 0.86 EDNRA (0.43) MAPTKDM4ENPC1ALDH1A1EDNRA
Ammonia Solution, Strong SCHEMBL9536160 0.85 EDNRA (0.42) MAPTEDNRAFABP4
SCHEMBL66383 0.85 CA1 (0.42) MAPT
SCHEMBL29368060 0.85 CA1 (0.42) MAPT
SCHEMBL66269 0.84 MAPT (0.46) MAPTKDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11898955-B2 Devices, systems, and methods for agrochemical detection and agrochemical compositions SPOGEN BIOTECH INC. (US) 2024-02-13 US disclosed
US-20230152217-A1 DEVICES, SYSTEMS, AND METHODS FOR AGROCHEMICAL DETECTION AND AGROCHEMICAL COMPOSITIONS SPOGEN BIOTECH INC. 2023-05-18 US disclosed
US-20210080385-A1 DEVICES, SYSTEMS, AND METHODS FOR AGROCHEMICAL DETECTION AND AGROCHEMICAL COMPOSITIONS GENISYS CREDIT UNION 2021-03-18 US disclosed
US-10788419-B2 Devices, systems, and methods for agrochemical detection and agrochemical compositions SPOGEN BIOTECH INC. (US) 2020-09-29 US disclosed
US-10448638-B2 Synergistic weed control from applications of pyridine carboxylic acid herbicides and ALS inhibitors DOW AGROSCIENCES LLC (US) 2019-10-22 US disclosed
US-20180364155-A1 DEVICES, SYSTEMS, AND METHODS FOR AGROCHEMICAL DETECTION AND AGROCHEMICAL COMPOSITIONS GENISYS CREDIT UNION 2018-12-20 US disclosed
US-20160135457-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND ALS INHIBITORS DOW AGROSCIENCES 2016-05-19 US disclosed
US-20130254944-A1 Herbicide Tolerant Soybeans and Methods of Use E.I. DU PONT DE NEMOURS AND COMPANY (US) 2013-09-26 US disclosed
EP-2254418-A2 METHOD OF CONTROLLING UNWANTED VEGETATION Arysta LifeScience North America, LLC (US) 2010-12-01 EP disclosed
WO-2009102689-A2 METHOD OF CONTROLLING UNWANTED VEGETATION ARYSTA LIFESCIENCE NORTH AMERICA, LLC (US) 2009-08-20 WO disclosed
US-20090203526-A1 METHOD OF CONTROLLING UNWANTED VEGETATION ARYSTA LIFESCIENCE NORTH AMERICA, LLC 2009-08-13 US disclosed
US-20040110637-A1 Method of safening crops using isoxazoline carboxylates BAYER CROPSCIENCE GMBH (DE) 2004-06-10 US disclosed
EP-1365648-A1 METHOD OF SAFENING CROPS USING ISOXAZOLINE CARBOXYLATES Bayer CropScience GmbH (DE) 2003-12-03 EP disclosed
WO-2002060256-A1 METHOD OF SAFENING CROPS USING ISOXAZOLINE CARBOXYLATES BAYER CROPSCIENCE GMBH (DE) 2002-08-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160135457-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND ALS INHIBITORS NOTUM, ABAT, SOD1 MAPT 149/4885KDM4E 2442/4885NPC1 3727/4885
US-10448638-B2 Synergistic weed control from applications of pyridine carboxylic acid herbicides and ALS inhibitors NOTUM, ABAT, SOD1 MAPT 149/4885KDM4E 2442/4885NPC1 3727/4885
US-20130254944-A1 Herbicide Tolerant Soybeans and Methods of Use HACL2, AGXT, PFAS MAPT 4564/4885KDM4E 4443/4885NPC1 4587/4885
US-20040110637-A1 Method of safening crops using isoxazoline carboxylates CYP2W1, CYP4Z1, CYP4X1 MAPT 4649/4885KDM4E 3471/4885NPC1 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.