Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1293374 | 0.95 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1718932 | 0.86 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL17751332 | 0.82 | TSHR (0.45) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7629287 | 0.81 | TSHR (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1455777 | 0.80 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10793367 | 0.79 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16486229 | 0.79 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11442386 | 0.79 | TSHR (0.56) | TSHRTHRBALDH1A1CYP3A4 | |
| SCHEMBL28548008 | 0.79 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL12701957 | 0.78 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476824-B | Two-component plaster material and use thereof | 喜利得股份公司 | 2021-03-09 | — | — | CN | claimed |
| EP-0059528-B1 | POLYSILOXANE WITH POLYCYCLIC MODIFIER COMPOSITION AND BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 1986-04-16 | — | — | EP | claimed |
| US-4355147-A | ESPECIALLY CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1982-10-19 | — | — | US | claimed |
| EP-0059528-A1 | Polysiloxane with polycyclic modifier composition and biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1982-09-08 | — | — | EP | claimed |
| CN-102197093-A | Metallized particles formed from a dispersion | DOW CORNING | 2011-09-21 | — | — | CN | disclosed |
| WO-2009085642-A1 | TRIMETHYLSILYL-CAPPED POLYSILOXANE MACROMONOMERS CONTAINING POLAR FLUORINATED SIDE-CHAINS | BAUSCH & LOMB INCORPORATED (US) | 2009-07-09 | — | — | WO | disclosed |
| US-20090168013-A1 | Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains | BAUSCH & LOMB INCORPORATED | 2009-07-02 | — | — | US | disclosed |
| CN-1162472-C | Contact lens material | ʿ | 2004-08-18 | — | — | CN | disclosed |
| US-6730767-B2 | OPTICAL TRANSPARENT; BIOCOMPATIBLE MEDICAL EQUIPMENT | BAUSCH & LOMB INCORPORATED | 2004-05-04 | — | — | US | disclosed |
| EP-1019416-B1 | LOW WATER POLYMERIC SILICONE COMPOSITIONS HAVING REDUCED MODULUS | BAUSCH & LOMB (US) | 2003-01-22 | — | — | EP | disclosed |
| CN-1373794-A | Contact lens material | BAUSCH & LOMB (US) | 2002-10-09 | — | — | CN | disclosed |
| EP-0865444-B1 | MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF SILICONE HYDROGELS | BAUSCH & LOMB (US) | 2001-09-19 | — | — | EP | disclosed |
| EP-0059528-B1 | POLYSILOXANE WITH POLYCYCLIC MODIFIER COMPOSITION AND BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0124017-A2 | Polysiloxane composition with improved surface wetting characteristics and biomedical devices made thereof | BAUSCH & LOMB INCORPORATED (US) | 1984-11-07 | — | — | EP | disclosed |
| EP-0035080-B1 | SHAPED BIOMEDICAL ARTICLES FORMED FROM POLYSILOXANE POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 1984-08-15 | — | — | EP | disclosed |
| US-4355147-A | ESPECIALLY CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1982-10-19 | — | — | US | disclosed |
| EP-0059528-A1 | Polysiloxane with polycyclic modifier composition and biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1982-09-08 | — | — | EP | disclosed |
| EP-0059529-A1 | Polysiloxane composition and biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1982-09-08 | — | — | EP | disclosed |
| EP-0035080-A1 | Shaped biomedical articles formed from polysiloxane polymers | BAUSCH & LOMB INCORPORATED (US) | 1981-09-09 | — | — | EP | disclosed |
| US-4195030-A | Preparation of monomeric organosilicon esters | BAUSCH & LOMB INCORPORATED (US) | 1980-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090168013-A1 | Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains | VCL, PCNA, MLEC | TSHR 2596/4885POLB 2493/4885APEX1 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.