Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980313 | 0.82 | CYP2A6 (0.43) | CYP2A6KDM4EMAPTERN1TDP1 | |
| SCHEMBL6975978 | 0.78 | CYP2A6 (0.44) | CYP2A6KDM4EMAPTERN1ALDH1A1 | |
| SCHEMBL6984412 | 0.78 | CYP2A6 (0.47) | CYP2A6KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL7067833 | 0.78 | ERN1 (0.47) | CYP2A6KDM4EERN1 | |
| SCHEMBL6973728 | 0.78 | CYP2A6 (0.43) | CYP2A6KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL31280833 | 0.78 | CYP2A6 (0.43) | CYP2A6ERN1 | |
| SCHEMBL24799787 | 0.74 | ERN1 (0.43) | CYP2A6KDM4EMAPTERN1TDP1 | |
| SCHEMBL7067241 | 0.74 | CA1 (0.42) | CYP2A6KDM4EMAPTERN1ALDH1A1 | |
| SCHEMBL26491612 | 0.74 | CYP2A6 (0.40) | CYP2A6KDM4EMAPTERN1ALDH1A1 | |
| SCHEMBL2263913 | 0.73 | CYP2A6 (0.57) | CYP2A6KDM4EMAPTERN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132213-B1 | SILYLETHYNYLATED HETEROACENES AND ELECTRONIC DEVICES MADE THEREWITH | UNIV KENTUCKY RES FOUND (US) | 2013-05-15 | — | — | EP | disclosed |
| EP-2132213-A1 | SILYLETHYNYLATED HETEROACENES AND ELECTRONIC DEVICES MADE THEREWITH | University of Kentucky Research Foundation (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008107089-A1 | SILYLETHYNYLATED HETEROACENES AND ELECTRONIC DEVICES MADE THEREWITH | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2008-09-12 | — | — | WO | disclosed |
| US-7385221-B1 | Silylethynylated heteroacenes and electronic devices made therewith | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2008-06-10 | — | — | US | disclosed |
| US-20080128680-A1 | SILYLETHYNYLATED HETEROACENES AND ELECTRONIC DEVICES MADE THEREWITH | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2008-06-05 | — | — | US | disclosed |