SCHEMBL4444977

SCHEMBL4444977

C=C(Cl)C(=O)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4444781 1.00 THRB (0.35) THRB
SCHEMBL4440813 1.00 THRB (0.35) THRB
SCHEMBL4444226 1.00 THRB (0.35) THRB
SCHEMBL4390006 0.83 THRB (0.38) THRB
SCHEMBL4401769 0.83 THRB (0.38) THRB
SCHEMBL4400459 0.83 THRB (0.38) THRB
SCHEMBL7712281 0.83 THRB (0.38) THRB
SCHEMBL24499062 0.83
SCHEMBL29794001 0.82 THRB (0.34) THRB
SCHEMBL28444910 0.82 THRB (0.34) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2276781-B1 ETHYLENE-TETRAFLUOROETHYLENE INTERMEDIATES DU PONT (US) 2012-11-07 EP disclosed
US-8212064-B2 Ethylene tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-03 US disclosed
US-20090287010-A1 Ethylene-tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-19 US disclosed