Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 12/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4448463 | 0.99 | NSD2 (0.53) | NSD2SLC1A3SLC1A2SLC1A1TTR | |
| SCHEMBL4449277 | 0.82 | NSD2 (0.56) | NSD2TTREDNRA | |
| SCHEMBL16000118 | 0.80 | NSD2 (0.64) | NSD2TTREDNRA | |
| SCHEMBL4445405 | 0.79 | EDNRA (0.47) | SLC1A3SLC1A2SLC1A1EDNRA | |
| SCHEMBL25155956 | 0.79 | IDH1 (0.49) | — | |
| SCHEMBL30344877 | 0.79 | IDH1 (0.49) | — | |
| SCHEMBL27232659 | 0.79 | IDH1 (0.49) | — | |
| SCHEMBL30966475 | 0.79 | IDH1 (0.49) | — | |
| SCHEMBL12462066 | 0.78 | KEAP1 (0.50) | — | |
| SCHEMBL12462064 | 0.78 | KEAP1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |
| EP-1402890-B1 | SULFONAMIDE DERIVATIVES | INST MED MOLECULAR DESIGN INC (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1402890-A1 | SULFONAMIDE DERIVATIVES | Institute of Medicinal Molecular Design, Inc. (JP) | 2004-03-31 | — | — | EP | disclosed |