SCHEMBL4445302

SCHEMBL4445302

[O]C(F)(F)C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL146151 0.78
SCHEMBL9386556 0.78
SCHEMBL4245205 0.78
SCHEMBL20529345 0.75
SCHEMBL9066678 0.70 ALDH1A1 (0.54)
SCHEMBL1479028 0.70
SCHEMBL65852 0.70
SCHEMBL5080332 0.67
SCHEMBL339702 0.67
SCHEMBL10965452 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104230770-A Styryl sulfone compound, preparation method and application thereof as neuroprotective agent HUAXIASHENGSHENG PHARMACEUTICAL BEIJING CO LTD 2014-12-24 CN claimed
EP-1969939-A2 Nematicidal compositions Devgen NV (BE) 2008-09-17 EP claimed
US-20080146445-A1 Nematicidal Compositions DEVGEN NV (BE) 2008-06-19 US claimed
US-5237099-A Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2-alkyl and 2-cycloalkylhydrazides AMERICAN CYANAMID COMPANY (US) 1993-08-17 US claimed
EP-0392241-B1 SUBSTITUTED 1-ARYLPYRAZOLS BAYER AG (DE) 1993-06-02 EP claimed
EP-0257296-B1 4-CYANO(NITRO)-5-OXY(THIO)-PYRAZOLE DERIVATIVES BAYER AG (DE) 1993-05-12 EP claimed
EP-0320750-B1 PROCESS FOR THE PREPARATION OF 4-SUBSTITUTED-3-METHYL-1-ARYL-5-AMINO-PYRAZOLES BAYER AG (DE) 1993-02-03 EP claimed
EP-0228564-B1 NOVEL INSECTICIDAL DIACYLHYDRAZINE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1992-01-29 EP claimed
EP-0235628-B1 1-ARYLPYRAZOLES BAYER AG (DE) 1991-04-24 EP claimed
US-4971989-A PESTICIDES, MITICIDES, INSECTICIDES AND NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-11-20 US claimed
EP-0205024-A2 5-Amino-4-heterocyclyl-1-pyridyl-pyrazoles BAYER AG (DE) 1986-12-17 EP claimed
EP-0205021-A2 5-Amino-4-cyano-1-pyridyl pyrazoles BAYER AG (DE) 1986-12-17 EP claimed
EP-0205022-A2 1-Aryl-5-alkoximinoalkyl amino pyrazoles BAYER AG (DE) 1986-12-17 EP claimed
US-4614533-A Herbicidal 5-amino-1-phenylpyrazoles BAYER AKTIENGESELLSCHAFT (DE) 1986-09-30 US claimed
US-4614534-A HERBICIDES, PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1986-09-30 US claimed
EP-0192951-A2 5-Sulfonamido-1-aryl pyrazoles BAYER AG (DE) 1986-09-03 EP claimed
EP-0191282-A1 1-Aryl-4-nitropyrazoles BAYER AG (DE) 1986-08-20 EP claimed
US-4533676-A 2,5-Dihalogenobenzoyl-(thio)urea insecticides BAYER AKTIENGESELLSCHAFT (DE) 1985-08-06 US claimed
EP-0132680-A1 Substituted furazans BAYER AG (DE) 1985-02-13 EP claimed
EP-0093976-A1 2,4-Dihalogenbenzoyl ureas and thioureas, processes for their preparation and their use as pesticides BAYER AG (DE) 1983-11-16 EP claimed