SCHEMBL4445387

SCHEMBL4445387

Nc1cccc2c(S(=O)(=O)NCc3ccc(O)c(O)c3)cccc12

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 16/20 0.68
TTR P02766 1/20 0.47
KDM4E B2RXH2 1/20 0.44
NPY5R Q15761 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4448330 0.99 NSD2 (0.69) NSD2TTRKDM4ENPY5R
SCHEMBL4477881 0.88 NSD2 (0.51) NSD2KDM4E
SCHEMBL4449055 0.86 NSD2 (0.68) NSD2
SCHEMBL4445813 0.86 NSD2 (0.73) NSD2TTRNPY5R
Hydrochloric Acid SCHEMBL4445423 0.85 NSD2 (0.69) NSD2
Hydrochloric Acid SCHEMBL4441213 0.85 NSD2 (0.74) NSD2TTRNPY5R
SCHEMBL4443035 0.83 NSD2 (0.77) NSD2TTRNPY5R
SCHEMBL4450802 0.82 NSD2 (0.82) NSD2TTRNPY5R
SCHEMBL4447190 0.82 NSD2 (0.71) NSD2NPY5R
SCHEMBL4444964 0.82 NSD2 (0.68) NSD2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7547716-B2 Sulfonamide derivatives INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2009-06-16 US claimed