Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 16/20 | 0.82 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4445018 | 0.99 | NSD2 (0.82) | NSD2NPY5RCA12CA1CA2 | |
| SCHEMBL4445013 | 0.90 | NSD2 (1.00) | NSD2CA1CA2CA9 | |
| SCHEMBL4441197 | 0.90 | NSD2 (1.00) | NSD2NPY5R | |
| SCHEMBL4443335 | 0.89 | NSD2 (0.78) | NSD2 | |
| Hydrochloric Acid SCHEMBL4445433 | 0.89 | NSD2 (1.00) | NSD2CA1CA2CA9 | |
| SCHEMBL4454417 | 0.89 | NSD2 (0.78) | NSD2 | |
| Hydrochloric Acid SCHEMBL4444954 | 0.87 | NSD2 (0.78) | NSD2 | |
| Hydrochloric Acid SCHEMBL4446935 | 0.87 | NSD2 (0.78) | NSD2 | |
| SCHEMBL4444949 | 0.87 | NSD2 (0.84) | NSD2NPY5R | |
| SCHEMBL4450751 | 0.87 | NSD2 (0.76) | NSD2CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | disclosed |
| EP-1402890-B1 | SULFONAMIDE DERIVATIVES | INST MED MOLECULAR DESIGN INC (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1402890-A1 | SULFONAMIDE DERIVATIVES | Institute of Medicinal Molecular Design, Inc. (JP) | 2004-03-31 | — | — | EP | disclosed |