Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 16/20 | 0.65 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4444627 | 0.99 | NSD2 (0.65) | NSD2NPY1RNPY5RNAMPT | |
| SCHEMBL4443030 | 0.85 | NSD2 (0.74) | NSD2TTR | |
| SCHEMBL4483058 | 0.85 | NPY1R (0.49) | NSD2NPY1RNPY5RNAMPT | |
| Hydrochloric Acid SCHEMBL4444986 | 0.84 | NSD2 (0.74) | NSD2TTR | |
| SCHEMBL4445041 | 0.83 | NSD2 (0.67) | NSD2 | |
| Hydrochloric Acid SCHEMBL4450842 | 0.82 | NSD2 (0.68) | NSD2 | |
| SCHEMBL4449107 | 0.82 | NSD2 (0.68) | NSD2NPY5R | |
| SCHEMBL4443339 | 0.81 | NSD2 (0.67) | NSD2 | |
| Hydrochloric Acid SCHEMBL4449077 | 0.81 | NSD2 (0.69) | NSD2 | |
| SCHEMBL4443417 | 0.81 | NSD2 (0.67) | NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |
| EP-1402890-B1 | SULFONAMIDE DERIVATIVES | INST MED MOLECULAR DESIGN INC (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1402890-A1 | SULFONAMIDE DERIVATIVES | Institute of Medicinal Molecular Design, Inc. (JP) | 2004-03-31 | — | — | EP | disclosed |