Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 15/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4450842 | 0.99 | NSD2 (0.68) | NSD2LMNAKDM4EBRD4KMT2A | |
| SCHEMBL4443030 | 0.89 | NSD2 (0.74) | NSD2 | |
| Hydrochloric Acid SCHEMBL4444986 | 0.87 | NSD2 (0.74) | NSD2 | |
| SCHEMBL4454452 | 0.86 | NSD2 (0.71) | NSD2KDM4E | |
| SCHEMBL4449107 | 0.85 | NSD2 (0.68) | NSD2KDM4E | |
| Hydrochloric Acid SCHEMBL4452891 | 0.85 | NSD2 (0.71) | NSD2KDM4E | |
| Hydrochloric Acid SCHEMBL4449077 | 0.84 | NSD2 (0.69) | NSD2KDM4E | |
| SCHEMBL4443339 | 0.84 | NSD2 (0.67) | NSD2KMT2A | |
| SCHEMBL4443417 | 0.84 | NSD2 (0.67) | NSD2KDM4E | |
| SCHEMBL4445810 | 0.83 | NSD2 (0.65) | NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |