⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13882758 | 0.79 | — | — | |
| SCHEMBL4445856 | 0.79 | — | — | |
| SCHEMBL10048289 | 0.75 | — | — | |
| SCHEMBL3634744 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL3624139 | 0.72 | — | — | |
| SCHEMBL7965206 | 0.72 | — | — | |
| SCHEMBL7078217 | 0.71 | — | — | |
| SCHEMBL674916 | 0.71 | — | — | |
| SCHEMBL8077178 | 0.71 | — | — | |
| SCHEMBL12443435 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506368-B | Transduction of transport nucleic acids by reversible phosphotriester charge neutralization protecting groups | 加利福尼亚大学董事会 | 2017-02-08 | — | — | CN | disclosed |
| EP-2046964-A2 | TRANSDUCIBLE DELIVERY OF NUCLEIC ACIDS BY REVERSIBLE PHOSPHOTRIESTER CHARGE NEUTRALIZATION PROTECTING GROUPS | The Regents of the University of California (US) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008008476-A2 | TRANSDUCIBLE DELIVERY OF NUCLEIC ACIDS BY REVERSIBLE PHOSPHOTRIESTER CHARGE NEUTRALIZATION PROTECTING GROUPS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-01-17 | — | — | WO | disclosed |