Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20582043 | 0.86 | HTT (0.43) | TSHRSPHK1 | |
| SCHEMBL28933239 | 0.83 | ALDH1A1 (0.41) | TSHRALDH1A1CA1CA2SPHK1 | |
| SCHEMBL22117615 | 0.82 | KMT2A (0.43) | TSHRALDH1A1 | |
| SCHEMBL4342842 | 0.78 | ADRB2 (0.33) | TSHRADRB2ADRB1ADRB3CA1 | |
| SCHEMBL3634742 | 0.78 | ADRB2 (0.33) | TSHRADRB2ADRB1ADRB3CA1 | |
| SCHEMBL18104322 | 0.77 | ADRB2 (0.32) | ADRB2ADRB1ADRB3CA1CA2 | |
| SCHEMBL10048289 | 0.77 | — | — | |
| SCHEMBL3835007 | 0.74 | TSHR (0.34) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL31465117 | 0.73 | SPHK1 (0.36) | TSHRCA1CA2SPHK1 | |
| SCHEMBL4445861 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103707-A1 | MONO-AND DI-PHOSPHATES OF 3-(3-FLUORO-4-HYDROXY-PHENYL)-7-HYDROXY-NAPHTHALENE-1-CARBONITRILE | WYETH (US) | 2008-08-28 | — | — | WO | claimed |
| EP-4719608-A1 | QUINAZOLINYL-INDAZOLE DERIVATIVES AS THERAPEUTIC COMPOUNDS FOR HIV | GILEAD SCIENCES, INC. (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4612156-A1 | ANTI-VIRAL COMPOUNDS | Aligos Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024249592-A1 | QUINAZOLINYL-INDAZOLE DERIVATIVES AS THERAPEUTIC COMPOUNDS FOR HIV | GILEAD SCIENCES, INC. (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024097296-A1 | ANTI-VIRAL COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2023140369-A1 | PHOSPHORIC ACID DERIVATIVES | Prism BioLab Co., Ltd. (JP) | 2023-07-27 | — | — | WO | disclosed |
| EP-3864003-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3044211-A1 | ANTIBACTERIAL 2H-INDAZOLE DERIVATIVES | Actelion Pharmaceuticals Ltd (CH) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015036964-A1 | ANTIBACTERIAL 2H-INDAZOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2015-03-19 | — | — | WO | disclosed |
| CN-104105691-A | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC | 2014-10-15 | — | — | CN | disclosed |
| WO-2005086638-A2 | ANALOGS EXHIBITING INHIBITION OF CELL PROLIFERATION, METHODS OF MAKING, AND USES THEREOF | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-09-22 | — | — | WO | disclosed |
| CN-1196719-C | Procatalysts including bidentate ligands, catalyst systems and their use in olefin polymerization | EASTMAN CHEM CO (US) | 2005-04-13 | — | — | CN | disclosed |
| CN-1144821-C | Procatalysts comprising bidentate ligands, catalyst systems, and use in olefin polymerization | 伊斯曼化学公司 | 2004-04-07 | — | — | CN | disclosed |
| EP-1377556-A1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | Pfizer Limited (GB) | 2004-01-07 | — | — | EP | disclosed |
| CN-1416439-A | Procatalysts including bidentate ligands, catalyst systems and their use in olefin polymerization | EASTMAN CHEM CO (US) | 2003-05-07 | — | — | CN | disclosed |
| CN-1416440-A | Procatalysts catalyst systems, and use in olefin polymerization | EASTMAN CHEM CO (US) | 2003-05-07 | — | — | CN | disclosed |
| CN-1394212-A | Procatalysts comprising bidentate ligands, catalyst systems, and use in olefin polymerization | EASTMAN CHEM CO (US) | 2003-01-29 | — | — | CN | disclosed |
| WO-2002085860-A1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LIMITED (GB) | 2002-10-31 | — | — | WO | disclosed |
| EP-0821696-A1 | PEPTIDE ANTAGONISTS OF CELLULAR MITOGENESIS AND MOTOGENESIS AND THEIR THERAPEUTIC USE | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-02-04 | — | — | EP | disclosed |
| WO-1997030079-A1 | PEPTIDE ANTAGONISTS OF CELLULAR MITOGENESIS AND MOTOGENESIS AND THEIR THERAPEUTIC USE | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-08-21 | — | — | WO | disclosed |