SCHEMBL44459

SCHEMBL44459

O=c1[nH]cc(CO)c(=O)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.52
MAPT P10636 2/20 0.48
DPYD Q12882 1/20 0.46
ATAD2 Q6PL18 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
CYP19A1 P11511 1/20 0.46
TSHR P16473 1/20 0.46
THPO P40225 1/20 0.46
MTOR P42345 1/20 0.46
HTT P42858 1/20 0.46
HBB P68871 1/20 0.46
PMP22 Q01453 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GRIA1 P42261 1/20 0.45
GRIA2 P42262 1/20 0.45
GRIA3 P42263 1/20 0.45
GRIA4 P48058 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11272295 0.98 GAA (0.50) GAAMAPTDPYDATAD2ALDH1A1
Water SCHEMBL6482818 0.98 GAA (0.50) GAAMAPTDPYDATAD2ALDH1A1
Phosphoric Acid SCHEMBL29493371 0.92 GAA (0.45) GAAMAPTDPYDATAD2ALDH1A1
SCHEMBL28633880 0.90 GAA (0.44) GAAMAPTDPYD
Uracil SCHEMBL29116490 0.86 CRBN (0.57) GAAMAPT
SCHEMBL7070324 0.83 GAA (0.50) GAAMAPTDPYDATAD2ALDH1A1
SCHEMBL29002023 0.82 GAA (0.37) GAAMAPT
SCHEMBL29266086 0.82 GAA (0.37) GAAMAPT
SCHEMBL4940336 0.82 GAA (0.37) GAAMAPTDPYD
SCHEMBL4353311 0.81 DPYD (0.50) GAAMAPTDPYDATAD2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6389 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-12618064-B2 Acetylated ribonucleic acids and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2026-05-05 US claimed
US-20260098287-A1 METHOD AND KIT FOR REGENERATING REUSABLE INITIATORS FOR NUCLEIC ACID SYNTHESIS CHENG-YAO CHEN (TW) 2026-04-09 US claimed
EP-4720331-A1 FALSE POSITIVE REDUCTION BY TRANSLESION POLYMERASE REPAIR Illumina, Inc. (US) 2026-04-08 EP claimed
CN-121574134-A Preparation method of treasipril and salt thereof 济南圣泉集团股份有限公司 2026-02-27 CN claimed
US-12559515-B2 Cap compounds and RNAS comprising the same HELIX NANOTECHNOLOGIES INC (US) 2026-02-24 US claimed
WO-1992015707-A1 IMMUNOASSAY FOR ANTIBODIES TO OXIDIZED DNA AND USES THEREOF NEW YORK UNIVERSITY (US) 1992-09-17 WO claimed
EP-0195346-B1 3-ARYL URACILES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1992-06-24 EP claimed
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US claimed
US-4987065-A GENETIC ENGINEERING ENZO BIOCHEM, INC. (US) 1991-01-22 US claimed
EP-0173251-B1 NUCLEIC-ACIDS SEQUENCE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE DETERMINATION OF NUCLEIC ACIDS Roche Diagnostics GmbH (DE) 1989-11-23 EP claimed
EP-0122151-B1 PRODUCTION OF PRIMARY OR SECONDARY ALCOHOL DERIVATIVES OF PHOSPHOLIPIDS BY THE ENZYMATIC TECHNIQUE MEITO SANGYO KABUSHIKI KAISHA (JP) 1989-02-15 EP claimed
US-4783402-A Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1988-11-08 US claimed
CN-86101792-A The preparation method of heterogeneous ring compound 1986-11-12 CN claimed
EP-0195346-A2 3-Aryl uraciles and their use as herbicides CIBA-GEIGY AG (CH) 1986-09-24 EP claimed
EP-0122151-A2 Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1984-10-17 EP claimed