SCHEMBL28633880

SCHEMBL28633880

NCc1c[nH]c(=O)[nH]c1=O.O=c1[nH]cc(CO)c(=O)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.44
MAPT P10636 1/20 0.42
DPYD Q12882 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2037916 0.90 DPYD (0.46) GAAMAPTDPYD
SCHEMBL44459 0.90 GAA (0.52) GAAMAPTDPYD
Hydrochloric Acid SCHEMBL22659843 0.88 DPYD (0.45) GAAMAPTDPYD
Water SCHEMBL11272295 0.88 GAA (0.50) GAAMAPTDPYD
Water SCHEMBL6482818 0.88 GAA (0.50) GAAMAPTDPYD
Phosphoric Acid SCHEMBL29493371 0.83 GAA (0.45) GAAMAPTDPYD
Uracil SCHEMBL29116490 0.77 CRBN (0.57) GAAMAPT
SCHEMBL29266086 0.77 GAA (0.37) GAAMAPT
SCHEMBL4940336 0.77 GAA (0.37) GAAMAPTDPYD
SCHEMBL29002023 0.77 GAA (0.37) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113286887-A Bispecific antisense oligonucleotides for dystrophin exon skipping 比奥马林技术公司 2021-08-20 CN disclosed