⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784425 | 1.00 | — | — | |
| SCHEMBL3784427 | 1.00 | — | — | |
| SCHEMBL17867727 | 0.80 | CHRM2 (0.41) | — | |
| SCHEMBL17880483 | 0.80 | CHRM2 (0.41) | — | |
| SCHEMBL10325720 | 0.80 | CD69 (0.39) | — | |
| SCHEMBL10325722 | 0.80 | CD69 (0.39) | — | |
| SCHEMBL10325721 | 0.80 | CD69 (0.39) | — | |
| SCHEMBL3783943 | 0.79 | PYGB (0.32) | — | |
| SCHEMBL4443930 | 0.79 | PYGB (0.32) | — | |
| SCHEMBL8008164 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150231195-A1 | COMPETITIVE INHIBITORS OF INVARIANT CHAIN EXPRESSION AND/OR ECTOPIC CLIP BINDING | REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-08-20 | — | — | US | disclosed |
| US-8557764-B2 | Methods of modulating immune function | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-10-15 | — | — | US | disclosed |
| US-20130259829-A1 | CLIP INHIBITORS AND METHODS OF MODULATING IMMUNE FUNCTION | VIRAL GENETICS, INC. (US) | 2013-10-03 | — | — | US | disclosed |
| EP-2633864-A1 | Clip inhibitors and methods of modulating immune function | The Regents of the University of Colorado (US) | 2013-09-04 | — | — | EP | disclosed |
| US-20090258027-A1 | Methods of modulating immune function | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-10-15 | — | — | US | disclosed |