Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13598955 | 0.80 | NQO2 (0.52) | EDNRAKDM1AMAOBMAOAEDNRB | |
| SCHEMBL27569651 | 0.76 | EDNRA (0.52) | EDNRAKDM1AMAOBMAOAEDNRB | |
| SCHEMBL13599076 | 0.76 | ESR2 (0.41) | ALDH1A1 | |
| SCHEMBL4420199 | 0.72 | EDNRA (0.48) | EDNRAMAOBMAOAEDNRBALDH1A1 | |
| SCHEMBL31132281 | 0.69 | KDM1A (0.62) | EDNRAKDM1AMAOBMAOAALDH1A1 | |
| SCHEMBL27910201 | 0.69 | KDM1A (0.62) | EDNRAKDM1AMAOBMAOAALDH1A1 | |
| SCHEMBL11824986 | 0.69 | SLC6A9 (0.57) | KDM1AMAOBMAOA | |
| SCHEMBL11824979 | 0.69 | SLC6A9 (0.57) | KDM1AMAOBMAOA | |
| SCHEMBL11824975 | 0.69 | SLC6A9 (0.57) | KDM1AMAOBMAOA | |
| SCHEMBL8946486 | 0.68 | MAPT (0.35) | MAOAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074102-A1 | 2-PHENYL INDENE DERIVATIVES USEFUL AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008043567-A1 | 2-PHENYL INDENE DERIVATIVES USEFUL AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2008-04-17 | — | — | WO | disclosed |