⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12478390 | 0.98 | — | — | |
| SCHEMBL474898 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL475088 | 0.79 | HTR1A (0.44) | — | |
| SCHEMBL5766231 | 0.78 | MAPT (0.43) | — | |
| SCHEMBL12309 | 0.77 | — | — | |
| SCHEMBL6676822 | 0.76 | HTR1A (0.52) | — | |
| SCHEMBL13593973 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL3447928 | 0.75 | — | — | |
| SCHEMBL3256199 | 0.75 | — | — | |
| SCHEMBL8128674 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255109-A1 | Non-peptide GnRH antagonists | VANTIA, LTD | 2008-10-16 | — | — | US | claimed |
| US-7365065-B2 | Non-peptide GnRH antagonists | FERRING B.V. (NL) | 2008-04-29 | — | — | US | claimed |
| EP-1485356-A1 | NON-PEPTIDE GnRH ANTAGONISTS | Ferring BV (NL) | 2004-12-15 | — | — | EP | claimed |
| WO-2003078398-A1 | NON-PEPTIDE GnRH ANTAGONISTS | FERRING BV (NL) | 2003-09-25 | — | — | WO | claimed |
| US-12116343-B2 | Inhibitors of APOL1 and methods of using same | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-10-15 | — | — | US | disclosed |
| WO-2023205415-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | MITOBRIDGE INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023154344-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| US-20220340523-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED | 2022-10-27 | — | — | US | disclosed |
| EP-3083619-B1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ASANA BIOSCIENCES LLC (US) | 2021-11-03 | — | — | EP | disclosed |
| WO-2021154997-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-08-05 | — | — | WO | disclosed |
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |
| US-20050222139-A1 | Non-peptide gnrh antagonists | FERRING B.V. (NL) | 2005-10-06 | — | — | US | disclosed |
| EP-1485356-A1 | NON-PEPTIDE GnRH ANTAGONISTS | Ferring BV (NL) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003078398-A1 | NON-PEPTIDE GnRH ANTAGONISTS | FERRING BV (NL) | 2003-09-25 | — | — | WO | disclosed |
| US-5288732-A | Fungicides for plants | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |
| US-5231109-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| EP-0259737-B1 | 2-CYANO-2-ALKOXIMINO-ACETAMIDE | BAYER AG (DE) | 1992-11-25 | — | — | EP | disclosed |
| US-4886833-A | FUNGICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| EP-0259737-A2 | 2-Cyano-2-alkoximino-acetamide | BAYER AG (DE) | 1988-03-16 | — | — | EP | disclosed |