Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340572 | 0.93 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL63717 | 0.91 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28347564 | 0.90 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16537369 | 0.88 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| Alcohol SCHEMBL28778173 | 0.88 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16286639 | 0.87 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16537816 | 0.87 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL221515 | 0.87 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| Butanone SCHEMBL28158317 | 0.87 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL486167 | 0.87 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589151-B2 | Thermoplastic resin composition and molded article comprising the same | MITSUBISHI RAYON CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |
| US-7186767-B2 | Poly(ester) carbonate molding compositions | BAYER AKTIENGESELLSCHAFT (DE) | 2007-03-06 | — | — | US | disclosed |
| US-20040106731-A1 | Poly(ester) carbonate molding compositions | COVESTRO DEUTSCHLAND AG (DE) | 2004-06-03 | — | — | US | disclosed |
| EP-0369376-A2 | Flame retardant polyphenylene ether resin composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-05-23 | — | — | EP | disclosed |