SCHEMBL486167

SCHEMBL486167

C=C(C)C(=O)OCCCC[Si](C)(OCC)OCC

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
THRB P10828 1/20 0.50
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.37
ACHE P22303 6/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16223360 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16223407 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16223551 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16223414 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16223299 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16223403 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16223433 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16537545 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16223450 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16223294 0.98 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101501088-B Silicone acrylate hybrid compositions DOW CORNING CORP. (US) 2011-11-30 CN claimed
CN-101501088-A Silicone acrylate hybrid compositions DOW CORNING (US) 2009-08-05 CN claimed
US-6281297-B1 CONTAINING ALLYL METHACRYLATE AND ORGANOSILICON COMPOUND KANEKA CORPORATION (JP) 2001-08-28 US claimed
CN-115516035-B Flame retardant polycarbonate compositions 科思创德国股份有限公司 2025-06-17 CN disclosed
CN-114729179-B Flame retardant polycarbonate-polyester blends 科思创德国股份有限公司 2024-07-05 CN disclosed
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN disclosed
EP-4153682-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-06-05 EP disclosed
US-20240174780-A1 HOLLOW PARTICLES AND USE THEREOF SEKISUI KASEI CO., LTD. (JP) 2024-05-30 US disclosed
EP-4153681-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-05-29 EP disclosed
US-11976189-B2 Thermoplastic resin composition and molded article TECHNO-UMG CO., LTD. (JP) 2024-05-07 US disclosed
US-20240052165-A1 RESIN COMPOSITION AND MOLDED BODY MITSUBISHI CHEMICAL CORPORATION (JP) 2024-02-15 US disclosed
US-4892900-A CONTAINING POLYSILOXANE GRAFT POLYMER, IMPROVED IMPACT STRENGTH MITSUBISHI RAYON CO., LTD. (JP) 1990-01-09 US disclosed
US-4888388-A BLENDS WITH POLYESTERS AND GRAFTED POLYSILOXANE-ACRYLIC POLYMERS MITSUBISHI RAYON COMPANY LIMITED (JP) 1989-12-19 US disclosed
EP-0326038-A1 An impact-resistant resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-08-02 EP disclosed
EP-0308871-A2 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-29 EP disclosed
EP-0307963-A2 Polycarbonate resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-22 EP disclosed
US-4775712-A BLENDS WITH POLYSILOXANES-IMPACT STRENGTH, HEAT AND COLD RESISTANT, WEATHERPROOFING-MOLDING MATERIALS MITSUBISHI RAYON CO., LTD. (JP) 1988-10-04 US disclosed
EP-0260552-A2 Graft copolymer rubber and polyphenylene ether resin composition comprising this rubber. MITSUBISHI RAYON CO., LTD. (JP) 1988-03-23 EP disclosed
US-4690986-A Impact-resistant thermoplastic polyorganosiloxane-based graft copolymer and process for producing same MITSUBISHI RAYON CO., LTD. (JP) 1987-09-01 US disclosed
EP-0231776-A1 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1987-08-12 EP disclosed