Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.44 |
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813866 | 0.88 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4444701 | 0.84 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL27937349 | 0.84 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL5417312 | 0.83 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL106698 | 0.81 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL29372465 | 0.81 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL2777176 | 0.81 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL4444755 | 0.80 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL4441567 | 0.78 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL1264001 | 0.78 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1256611-B1 | Aqueous dispersion and coated product | JSR CORP (JP) | 2009-07-29 | — | — | EP | disclosed |
| US-6726997-B2 | WWATERPROOF, HARDNESS, RATION TRANSPARENT; PROTECTIVE COATINGS | JSR CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20030073779-A1 | Aqueous dispersion and coated product | JSR CORPORATION (JP) | 2003-04-17 | — | — | US | disclosed |
| EP-1256611-A2 | Aqueous dispersion and coated product | JSR Corporation (JP) | 2002-11-13 | — | — | EP | disclosed |