Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29575333 | 0.85 | NPC1 (0.78) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL285733 | 0.85 | NPC1 (0.78) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4447229 | 0.84 | NPC1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4444755 | 0.83 | NPC1 (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4443402 | 0.81 | NPC1 (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL20363911 | 0.80 | NPC1 (0.64) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4445959 | 0.79 | NPC1 (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL20365735 | 0.79 | NPC1 (0.62) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4445489 | 0.77 | NPC1 (0.53) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2777176 | 0.76 | NPC1 (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1256611-B1 | Aqueous dispersion and coated product | JSR CORP (JP) | 2009-07-29 | — | — | EP | disclosed |
| US-6726997-B2 | WWATERPROOF, HARDNESS, RATION TRANSPARENT; PROTECTIVE COATINGS | JSR CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20030073779-A1 | Aqueous dispersion and coated product | JSR CORPORATION (JP) | 2003-04-17 | — | — | US | disclosed |
| EP-1256611-A2 | Aqueous dispersion and coated product | JSR Corporation (JP) | 2002-11-13 | — | — | EP | disclosed |