Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468905 | 0.86 | TP53 (0.69) | TP53TSHRADORA3CHRM1DRD3 | |
| SCHEMBL13453994 | 0.85 | TP53 (1.00) | TP53TSHRACACBPOLBCOPS5 | |
| SCHEMBL81866 | 0.85 | TP53 (1.00) | TP53TSHRACACBPOLBCOPS5 | |
| SCHEMBL16880397 | 0.85 | TP53 (1.00) | TP53TSHRACACBPOLBCOPS5 | |
| SCHEMBL21176929 | 0.84 | TP53 (0.72) | TP53TSHRADORA3CHRM1DRD3 | |
| SCHEMBL11553698 | 0.84 | TP53 (0.72) | TP53TSHRADORA3CHRM1DRD3 | |
| SCHEMBL11463307 | 0.83 | TP53 (0.66) | TP53TSHRADORA3CHRM1DRD3 | |
| SCHEMBL11460361 | 0.82 | TP53 (0.64) | TP53TSHRADORA3CHRM1DRD3 | |
| SCHEMBL9815067 | 0.82 | TSHR (0.74) | TP53TSHRLMNAESR1ESR2 | |
| Benzene SCHEMBL28938992 | 0.82 | TP53 (0.93) | TP53TSHRMAPTACACBCOPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279749-B | Synthetic method of 2-methyl-3- (4-tert-pentylphenyl) propanol | 镇江卡博医药科技有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-112279749-A | Synthetic method of 2-methyl-3- (4-tert-pentylphenyl) propanol | 镇江卡博医药科技有限公司 | 2021-01-29 | — | — | CN | claimed |
| US-20090131660-A1 | SYNTHESIS OF 3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPIONALDEHYDE AND cis-4--2,6-DIMETHYL-MORPHOLINE (AMOROLFINE) | GALDERMA S.A. (CH) | 2009-05-21 | — | — | US | claimed |
| EP-2007742-A1 | PROCESS FOR PRODUCING 3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPIONALDEHYDE AND CIS-4-{3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPYL}-2,6-DIMETHYL-MORPHOLINE (AMOROLFINE) | Galderma S.A. (CH) | 2008-12-31 | — | — | EP | claimed |
| WO-2007113218-A1 | PROCESS FOR PRODUCING 3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPIONALDEHYDE AND CIS-4-{3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPYL}-2,6-DIMETHYL-MORPHOLINE (AMOROLFINE) | GALDERMA S.A. (CH) | 2007-10-11 | — | — | WO | claimed |
| EP-1842848-A1 | Process for producing 3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propionaldehyde and cis-4{3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propyl}-2,6-dimethyl-morpholine (amorolfine) | Galderma S.A. (CH) | 2007-10-10 | — | — | EP | claimed |
| CN-112279749-B | Synthetic method of 2-methyl-3- (4-tert-pentylphenyl) propanol | 镇江卡博医药科技有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112279749-B | Synthetic method of 2-methyl-3- (4-tert-pentylphenyl) propanol | 镇江卡博医药科技有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112279749-A | Synthetic method of 2-methyl-3- (4-tert-pentylphenyl) propanol | 镇江卡博医药科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112279749-A | Synthetic method of 2-methyl-3- (4-tert-pentylphenyl) propanol | 镇江卡博医药科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| US-20090131660-A1 | SYNTHESIS OF 3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPIONALDEHYDE AND cis-4--2,6-DIMETHYL-MORPHOLINE (AMOROLFINE) | GALDERMA S.A. (CH) | 2009-05-21 | — | — | US | disclosed |
| US-20090131660-A1 | SYNTHESIS OF 3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPIONALDEHYDE AND cis-4--2,6-DIMETHYL-MORPHOLINE (AMOROLFINE) | GALDERMA S.A. (CH) | 2009-05-21 | — | — | US | disclosed |
| US-20090131660-A1 | SYNTHESIS OF 3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPIONALDEHYDE AND cis-4--2,6-DIMETHYL-MORPHOLINE (AMOROLFINE) | GALDERMA S.A. (CH) | 2009-05-21 | — | — | US | disclosed |
| EP-1842848-A1 | Process for producing 3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propionaldehyde and cis-4{3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propyl}-2,6-dimethyl-morpholine (amorolfine) | Galderma S.A. (CH) | 2007-10-10 | — | — | EP | disclosed |
| EP-1842848-A1 | Process for producing 3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propionaldehyde and cis-4{3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propyl}-2,6-dimethyl-morpholine (amorolfine) | Galderma S.A. (CH) | 2007-10-10 | — | — | EP | disclosed |
| EP-1842848-A1 | Process for producing 3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propionaldehyde and cis-4{3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propyl}-2,6-dimethyl-morpholine (amorolfine) | Galderma S.A. (CH) | 2007-10-10 | — | — | EP | disclosed |
| EP-0024334-B1 | MORPHOLINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-07-20 | — | — | EP | disclosed |
| EP-0024334-A1 | Morpholine derivatives, process for their production, pharmaceutical preparations containing these derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-03-04 | — | — | EP | disclosed |
| US-4202894-A | AGRICULTURE | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |
| EP-0005541-A2 | Substituted piperidine, morpholine or piperidone derivatives, fungicides containing these compounds, process for their preparation and their use, and the use of these compounds as fungicides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131660-A1 | SYNTHESIS OF 3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPIONALDEHYDE AND cis-4--2,6-DIMETHYL-MORPHOLINE (AMOROLFINE) | PDK2, EML4, DEK | TP53 3389/4885TSHR 4211/4885ADORA3 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.