SCHEMBL4447745

SCHEMBL4447745

[Zr]C(CC1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.44
HTR2A P28223 1/20 0.34
SIGMAR1 Q99720 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4475024 0.84 HTR6 (0.42) HTR6HTR2ASIGMAR1
SCHEMBL4468606 0.81 HTR6 (0.43) HTR6HTR2ASIGMAR1
SCHEMBL4462131 0.80 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL6856381 0.80 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL31124932 0.80 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL9226165 0.80 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL7208330 0.80 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL1539652 0.80 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL4466071 0.79 HTR2A (0.36) HTR6HTR2ASIGMAR1
SCHEMBL4474535 0.79 HTR6 (0.38) HTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0835886-B1 Process for preparing and using meso/racemic-(bis(indenyl)ethane)zirconium dichloride compounds ATOFINA RES (BE) 2004-02-25 EP claimed
EP-0775148-B2 BISCYCLOPENTADIENYL DIENE COMPLEXES DOW CHEMICAL CO (US) 2003-01-02 EP claimed
EP-1257587-A2 HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS THE DOW CHEMICAL COMPANY (US) 2002-11-20 EP claimed
US-6476283-B1 Hydrogenation of unsaturated polymers using divalent diene-containing bis-cyclopentadienyl group IV metal catalysts THE DOW CHEMICAL COMPANY 2002-11-05 US claimed
US-6465384-B1 BISCYCLOPENTADIENYL GROUP 4 TRANSITION METAL COMPLEXES POSSESSING DIENE LIGANDS AND TO USE AS POLYMERIZATION CATALYSTS THE DOW CHEMICAL COMPANY 2002-10-15 US claimed
WO-2001004164-A2 HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS THE DOW CHEMICAL COMPANY (US) 2001-01-18 WO claimed
EP-0775148-B1 BISCYCLOPENTADIENYL DIENE COMPLEXES DOW CHEMICAL CO (US) 1999-08-25 EP claimed
EP-0775148-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-05-28 EP claimed
WO-1996004290-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1996-02-15 WO claimed
EP-1377613-B1 METHOD OF MAKING INTERPOLYMERS AND PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-19 EP disclosed
US-RE43004-E1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC (US) 2011-12-06 US disclosed
US-7579407-B2 Thermoplastic elastomer compositions DOW GLOBAL TECHNOLOGIES INC. (US) 2009-08-25 US disclosed
US-7344775-B2 Isotactic propylene copolymer fibers, their preparation and use DOW GLOBAL TECHNOLOGIES INC. (US) 2008-03-18 US disclosed
EP-1724379-B1 Isotactic propylene homopolymer fibers and use DOW GLOBAL TECHNOLOGIES INC (US) 2008-01-02 EP disclosed
EP-0915098-A2 Biscyclopentadienyl diene complexes, their preparation and catalyst compositions containing them THE DOW CHEMICAL COMPANY (US) 1999-05-12 EP disclosed
US-5679816-A REACTING A GROUP 4 METAL SALT, A CONJUGATED DIENE, A REDUCING AGENT AND A CYCLOPENTADIENE COMPOUND THE DOW CHEMICAL COMPANY (US) 1997-10-21 US disclosed
EP-0775148-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-05-28 EP disclosed
US-5616664-A Polymerization process with biscyclopentadienyl diene complex containing catalysts THE DOW CHEMICAL COMPANY (US) 1997-04-01 US disclosed
US-5527929-A Zwitterionic biscyclopentadienyl complexes THE DOW CHEMICAL COMPANY (US) 1996-06-18 US disclosed
WO-1996004290-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1996-02-15 WO disclosed