SCHEMBL4447758

SCHEMBL4447758

NC(=O)C1=C(C(N)=O)CCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
USP2 O75604 1/20 0.37
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
F2 P00734 1/20 0.33
RECQL P46063 1/20 0.32
GABRR1 P24046 1/20 0.32
TRIM24 O15164 2/20 0.32
TRIM33 Q9UPN9 2/20 0.32
PARP1 P09874 1/20 0.32
PARP15 Q460N3 1/20 0.32
PARP10 Q53GL7 1/20 0.32
LMNA P02545 1/20 0.31
OR51E2 Q9H255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12475847 0.93 ALDH1A1 (0.37) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL4447755 0.89 PARP1 (0.42) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL4334172 0.89 PARP1 (0.42) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL11755833 0.86 ALDH1A1 (0.36) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL11755814 0.86 ALDH1A1 (0.36) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL10592697 0.83 POLB (0.33) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL671771 0.83 KDM4E (0.32) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL10017853 0.83 PARP1 (0.46) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL6886061 0.83 KDM4E (0.32) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL23291840 0.81 ALDH1A1 (0.31) ALDH1A1KDM4EMAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0635485-B1 TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEM RES (JP) 1997-06-11 EP claimed
US-5506190-A Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-04-09 US claimed
EP-0635485-A1 TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-01-25 EP claimed
EP-0198202-A2 Novel N-cyclohexyl-polycarboxamide compound and derivatives thereof, processes for preparing them, and use of them in preparation of host-guest complexes MITSUBISHI CORPORATION (JP) 1986-10-22 EP claimed
JP-54154737-A None JP disclosed
JP-6025127-A None JP disclosed
JP-55162756-A None JP disclosed
EP-4166329-A1 ETHYLENE-VINYL-ALCOHOL-BASED COPOLYMER RESIN COMPOSITION, MULTILAYER STRUCTURAL BODY, AND PACKAGING BODY Mitsubishi Chemical Corporation (JP) 2023-04-19 EP disclosed
US-20230080425-A1 ETHYLENE-VINYL ALCOHOL COPOLYMER RESIN COMPOSITION, MULTILAYER STRUCTURE, AND PACKAGE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-03-16 US disclosed
US-20090215192-A1 Solid-phase affinity-based method for preparing and manipulating an analyte-containing solution STRATOS BIOSYSTEMS, LLC (US) 2009-08-27 US disclosed
WO-2005118129-A1 SOLID-PHASE AFFINITY-BASED METHOD FOR PREPARING AND MANIPULATING AN ANALYTE-CONTAINING SOLUTION STRATOS BIOSYSTEMS, LLC (US) 2005-12-15 WO disclosed
US-6204222-B1 SUITABLE AS HERBICIDES AND FOR DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-20 US disclosed
JP-H0625127-A TETRAHYDROPHTHALAMIDE DERIVATIVE, ITS PRODUCTION AND HERBICIDE CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT SAGAMI CHEM RES CENTER 1994-02-01 JP disclosed
WO-1993019039-A1 TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1993-09-30 WO disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed
US-4613675-A HERBICIDES SANDOZ LTD. (CH) 1986-09-23 US disclosed
US-4613675-A HERBICIDES SANDOZ LTD. (CH) 1986-09-23 US disclosed
US-4613675-A HERBICIDES SANDOZ LTD. (CH) 1986-09-23 US disclosed
JP-S55162756-A PREPARATION OF CYCLOHEXENEDICARBOXYLIC ACID DIAMIDE MITSUBISHI CHEM IND LTD 1980-12-18 JP disclosed
JP-S54154737-A CYCLOHEXENEDICARBOXYLIC ACID DIAMIDE AND HERBICIDE MITSUBISHI CHEM IND LTD 1979-12-06 JP disclosed